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Latest Publications

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Neurosci Letter

Basmisanil, an α5-GABAAR negative allosteric modulator, produces rapid and sustained antidepressant-like responses in male mice.

2024

iScience

Myeloid-intrinsic cell cycle-related kinase drives immunosuppression to promote tumorigenesis

2023

FEMS Microbiology Reviews

The role of glycoconjugates as receptors for insecticidal proteins

2023

ACS Infectious Diseases

A Series of Spiropyrimidinetriones that Enhances DNA Cleavage Mediated by Mycobacterium tuberculosis Gyrase

2023

International Journal of Molecular Sciences

A 2.8 Å Structure of Zoliflodacin in a DNA Cleavage Complex with Staphylococcus aureus DNA Gyrase

2023

Journal of Medicinal Chemistry

Comparative Analysis of Small-Molecule LIMK1/2 Inhibitors: Chemical Synthesis, Biochemistry, and Cellular Activity

2022

Biomolecules

Neurosteroid Modulation of Synaptic and Extrasynaptic GABAA Receptors of the Mouse Nucleus Accumbens

2024

Biomolecules

Central Nervous System Targeted Protein Degraders

2023

Journal of Cell Science

The synthetic TRPML1 agonist ML-SA1 rescues Alzheimer-related alterations of the endosomal-autophagic-lysosomal system

2023

Frontiers in Cell and Developmental Biology

Charge and lipophilicity are required for effective block of the hair-cell mechano-electrical transducer channel by FM1-43 and its derivatives.

2023

Toxins

The Crystal Structure of Bacillus thuringiensis Tpp80Aa1 and Its Interaction with Galactose-Containing Glycolipids

2022

International Journal of Molecular Sciences

Oligonucleotide-Recognizing Topoisomerase Inhibitors (OTIs): Precision Gene Editors for Neurodegenerative Diseases?

2022

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Cardiff University

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United Kingdom

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